MATL 5979/6979: Biomaterials

Fall 2004

Course Content

Interactions between materials and proteins, cells, and tissue as related to medicine and biotechnology including tissue culture, cardiovascular, drug delivery, tissue engineering and other applications.  Thermodynamics of protein adsorption.  Cell biology of adhesion.  Analytical methods, sterilization, and regulations.

Course textbook: Biomaterials Science. An Introduction to Materials in Medicine. Editors: Buddy D. Ratner, A. Hoffman, F. Schoen, and J. Lemons. Academic Press, 1996, ICBN:0-12-582460-2Rolf E. Hummel, Electronic Properties of Materials, 3rd Ed., Springer-Verlag, Berlin, 2001.

Requirements and Evaluation for 5000 Level Students

Requirements: Good knowledge and understanding of fundamental principles of biomaterials. The ability to solve some mid-level problems presented in the textbook.

Evaluations:

Two take-home examinations consisting of data interpretation and essay-type questions.  Each exam will account for one-third of your grade.

One written paper and oral presentation.  The topic is up to the student, but must be approved by the instructor.  A 20 min. oral presentation covering your paper topic will be given to the class.  The paper and the presentation will be one-third of your grade (50/50).

Requirements and Evaluation for 6000 Level Students

Requirements: Deep knowledge of fundamental principles of biomaterials and its application. The ability to apply theoretical knowledge to solve all level problems presented in the textbook and additionally provided by instructor. In addition, accompanying knowledge of topics covered in journal articles from the following periodicals:  Journal of Biomedical Materials Research, Journal of Biomaterials Science, Biomaterials, Transactions of the American Society of Artificial Organs, Journal of Controlled Release, Tissue Engineering.

Evaluations:

Two take-home examinations consisting of data interpretation and essay-type questions.  Each exam will account for one-third of your grade.

One review paper suitable for submission to the Journal of Biomedical Materials Research and one oral presentation.  The topic is up to the student, but must be approved by the instructor.  A 25 min. oral presentation covering your paper topic will be given to the class.  The paper and the presentation will be one-third of your grade (50/50).