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Refereed Journal Publications
Electrochemical Properties of Interface Formed by Interlaced Layers of DNA- and Lysozyme-Coated Single-Walled Carbon Nanotubes,
Valber A. Pedrsosa§, Tony Gnanaprakasa§, Shankar Balasubramian, Eric V. Olsen, Virgina A.Davis ,
Aleksandr Simonian(§ - Authors contributed equally in this work). In Press, Electrochemistry Communications, 2009
Lysozyme Mediated Formation of Protein-Silica Nano-Composites for Biosensing Applications,
Madhumati Ramanathan, Heather R. Luckarift, Ainur Sarsenova, James R. Wild, Erlan K. Ramanculov, Eric V. Olsen, Aleksandr L. Simonian, In Press, Colloids and Surfaces: Biointerfaces, 2009
Copper nanoparticles and carbon nanotubes-based electrochemical sensing system for fast identification of tricresyl-phosphate in aqueous samples and air,
Valber Pedrosa, Rigved Epur, Jessica Benton, Ruel A. Overfelt, Aleksandr Simonian, In Press, Sensors Actuators B, 2009
Strong Antimicrobial Coatings:
Single-Walled Carbon Nanotubes Armored with Biopolymers, Dhriti Nepal§,
Shankar Balasubramanian§, Aleksandr Simonian and
Virginian Davis, Nano Letters, Vol 8, Issue 7, Pages:1896-1901 (§ - Authors contributed equally in this work).
Fluorescence-Based
Sensing of P-Nitrophenol and P-Nitrophenyl Substituent Organophosphates,
Sheetal Paliwal; Melinda Wales; Janet Grimsley; James Wild; Alex
Simonian. Analytica Chimica Acta, 2007, 596, pp.9-15.
Differential
effect of the shape of calcium alginate matrices on the physiology of
immobilized neuroblastoma N2a and Vero cells: a comparative study
Authors: S. Kintzios, I. Yiakoumetis, G. Moschopoulou, O. Mangana, K.
Nomikou, A. Simonian.
Biosensors
and Bioelectronics, 2007,
23, 543-548.
Optical leaky
waveguide biosensors for the detection of Organophosphorous pesticides,
M. Zourob, A. Simonian, J. Wild, S. Mohr, N. Goddard,
The Analyst,
2007, 132, pp.114 - 120.
Development
of a Surface Plasmon Resonance Biosensor for the Identification of
Campylobacter jejuni,
Dong Wei, Omar A. Oyarzabal, Tung-Shi
Huang, Shankar Balasubramanian, Srinivas Sista,
and Aleksandr L. Simonian, Journal of
Microbiological Methods 2007, 69, 78–85.
Highly
sensitive phage-based biosensor for the detection of beta-galactosidase,
Viswaprakash Nanduri, Shankar Balasubramanian, Srinivas Sista, Vitaly
J. Vodyanoy, Aleksandr L. Simonian Analytica Chimica
Acta, .2007,589, 166-172.
Enzyme-Encapsulated Silica Monolayers for Rapid Functionalization of a
Gold Surface,
H. Luckarift, S. Balasubramanian, S. Paliwal, G. Johnson and A.
Simonian, Colloids and Surfaces B: Biointerfaces,
2007, 58,
pp.28-33,
Invited publication.
Array biosensor based
on enzyme kinetics monitoring by fluorescence spectroscopy: Application
for neurotoxins detection, M. Ramanathan and A. L. Simonian,
Biosensors &
Bioelectronics,
Biosensors and Bioelectronics,
2007, 22, pp. 3001-3007.
Electrochemical Desorption of Proteins from
Gold Electrode Surface, Shankar Balasubramanian, Alexander Revzin,
Aleksandr Simonian, Electroanalysis, 2006. Invited
publication,
Volume 18, Issue 19-20, pp. 1885-1892.
Lytic Phage as a Specific and Selective
probe for detection of Staphylococcus aureus - A Surface Plasmon
Resonance Spectroscopic Study,
Shankar Balasubramanian; Iryna Sorokulova, Vitaly Vodyanoy,
Aleksandr Simonian. Biosensors & Bioelectronics
2007, 22, 948-955.
Phage as a Molecular Recognition Element in
Biosensors Immobilized by Physical Adsorption, Viswaprakash Nanduri,
Iryna B. Sorokulova, Alexandre Samoylov, Aleksandr Simonian,
Valery Petrenko, and Vitaly Vodyanoy, Biosensors & Bioelectronics,
2007, 22,
Issue 6, 15 January
2007, Pages 986-992.
TCP Electrochemical
Detection,” G. Vertelov, W. Gale, and A. Simonian, in: Chemical
Sensors and MEMS
ECS
Transactions, pp. 21-34, 2006
Development of a novel,
multi-analyte biosensor system for assaying cell division:
identification of cell proliferation/death precursor events.
S. Kintzios, I.
Marinopoulou, G. Moschopoulou, O. Mangana, K. Nomikou, K. Endo, I.
Papanastasiou, A.
Simonian.
Biosensors &
Bioelectronics, 2006, 21, pp.1365-1373.
A
Fluorescence-based Biosensor for the Detection of Organophosphate
Pesticides and Chemical Warfare Agents, L. Viveros, S. Paliwal, D.A.
McCrae, J. Wild, and A. Simonian. Sensors & Actuators B,
2006, 115, p.150-157.
Nanoparticle-based
Optical Biosensors for the Direct Detection of Organophosphate Chemical
Warfare Agents and Pesticides, A. L. Simonian, T. A. Good,
S.-S. Wang, and J. R. Wild.
Analytica Chimica Acta,
2005, Vol. 534, Issue 1, pp. 69-77.
Correlation Function and Spectral Density
of the Enzymatic Reaction Rate, V. B. Arakelyan, A. L. Simonian,
S. Kintzios, A. E. Gevorgyan, T. S. Sukiasyan, A. V. Arakelyan, E. S.
Gevorgyan. National Academy of Sciences of RA, Electronic Journal
of Natural Sciences, 2(5), 2005, pp. 3-7.
A FET-based Biosensor
for The Direct Detection of Organophosphate Neurotoxins,
A. L. Simonian,
A.W. Flounders, and J. R. Wild. Electroanalysis, 2004, 16,
p.1896-1906.
Study on the mechanism
of BERA (Bioelectric Recognition Assay): evidence for immobilized cell
membrane interactions with viral fragments, S. Kintzios, F. Bem, O.
Mangana, K. Nomikou, P., Markoulatos, N. Alexandropoulos , C. Fasseas,
V. Arakelyan, A-L.
Petrou, K. Soukouli, G.
Moschopoulou, A. Simonian.
Biosensors &
Bioelectronics, 2004,
Volume 20, Issue
4, 1 November 2004, Pages 907-916.
Control of Mammalian
Cell and Bacteria Adhesion on Substrates Micropatterned with
Poly(ethylene glycol) Hydrogels, Won-Gun Koh, Alexander Revzin,
Aleksandr Simonian,
Tony Reeves, and Michael Pishko, Biomedical Microdevices, 2003,
5:1, 11-19.
Characterization of Oxidoreductase/ Redox Polymer Electrostatic Film
Assembly by Surface Plasmon Resonance Spectroscopy, FTIR, and
Ellipsometry on Gold, A.L. Simonian, A. Revzin, J. R. Wild, J.
Elkind, and M. V. Pishko,
Analytica Chimica Acta,
2002, Vol. 466, 201-212.
Mass
Transfer in Amperometric Biosensors Based on Nanocomposite Thin Films of
Redox Polymers and Oxidoreductases, Michael V. Pishko, Alexander Revzin,
Aleksandr L.
Simonian.
Sensors, 2002, 2, 79-90
Glucose, Lactate, and Pyruvate Biosensor
Arrays Based on Redox Polymer/Oxidoreductase Nanocomposite Thin Films
Deposited on Photolithographically Patterned Gold Microelectrodes,
Alexander F. Revzin, Kaushik Sirkar, Aleksandr Simonian, and
Michael V. Pishko. Sensors and Actuators, B, 2002, Vol.81,
pp.359-368.
Discriminative Detection of Neurotoxins in
Multi-Component Samples, Simonian A. L., Efremenko E. N., and.
Wild J. R. Analytica Chimica Acta,
2001, Vol. 444, pp
179-186.
Enzyme-based biosensor for the direct detection of fluorine-containing
organophosphates, A.L. Simonian, J.K. Grimsley, A.W. Flounders
J. S. Schoeniger, Tu-Chen Cheng, J.J. DeFrank and J. R. Wild.
Analytica Chimica Acta, 2001, Vol. 442,
pp 15-23.
The Influence of
External Environment Fluctuations on the Signal Formation of
Microbiosensors, V B. Arakelian, J. R Wild, and A. L. Simonian.
Biosensors and Bioelectronics, 2001, Vol.16, #1, pp. 69-72.
Development of Sensors
for Direct Detection of Organophosphates; Sol-Gel Modified Field Effect
Transistor with Immobilized OPH, A. Flounders, A. Singh, J. Volponi, S.
Carichner, K. Wally, A. Simonian, J. Wild, J. Schoeniger,
Biosensors and Bioelectronics, 1999, Vol. 14, #8-9 pp, 713-720.
Poly(ethylene glycol)
Hydrogel-Encapsulated Fluorophore-Enzyme Conjugates for Direct Detection
of Organophosphorus Neurotoxins, R. Russell, M. Pishko, A. Simonian,
and J. Wild. Analytical Chemistry, 1999, Vol.71, pp.4909-4912.
An Enzyme Based
Biosensor for Direct Determination of Diisopropyl fluorophosphate,
A. L. Simonian, B. D. DiSioudi, and J. R. Wild,.
Analytica Chimica Acta,
1999, Vol. 389, No.1-3, pp. 189-196.
Investigation of
Stochastic Fluctuations in the Signal Formation of Microbiosensors, V B.
Arakelian, J. R Wild, and A. L. Simonian. Biosensors and
Bioelectronics, 1998, Vol. 13, No.1, 55-59.
New Concept for
Discriminative Biosensor: Detection of Organophosphates in the Presence
of Other Cholinesterases Inhibitors, A. L. Simonian, E. I.
Rainina, and J. R Wild. Analytical Letters, 1997, 30(14),
2453-2468.
A
Tryptophan-2-monooxygenase Based Amperometric Biosensor for L-tryptophan
Determination. Use of a Competitive Inhibitor as a Tool for Selectivity
Increase, A. L. Simonian, E. I. Rainina, P. F. Fitzpatrick, and
J. R Wild. Biosensors and Bioelectronics, 1997, Vol. 12, No.5
pp.363-371.
The Development of a
New Biosensor Based on Recombinant E.coli for the Detection of
Organophosphorus Neurotoxins, E.Rainina
, A.Simonian, A.Efremenco, S.Varfolomeyev and J.Wild ,
Biosensors and Bioelectronics, 1996. Vol. 11, No 10, pp. 991-1000.
Cell Biosensor for
Assay Phenol in Aqueous Solutions, E.I.Rainina, I.E.Badalian,
O.V.Ignatov, A.S.Fedorov, A. L. Simonian. Applied Biochemistry
and Biotechnology, 1996. V. 55, No 1. 117-127.
Flow-Injection
Amperometric Biosensor Based on Immobilized L-Lysineoxidase for L-Lysine
determination, A. L. Simonian, I. E.Badalian, T. T.Berezov, I.
P.Smirnova, S. H.Khaduev. Analytical Letters, 1994, V.27(15), pp.
2849 - 2860.
L-Lysine-2-monooxygenase Production by Some Strains of Pseudomonas
Fluorescens and Pseudomonas Putida Species, G. E.Khachatrian, A. L.
Simonian. World Journal of Microbiology&Biotechnology. 1994.
V.10, No. 6, pp. 711-712.
A Biosensor for
L-Proline Determination by Use of Immobilized Microbial Cells,
A.L.Simonian, I.E.Badalian, G.E.Khachatrian, S.Sh.Tatikian,
E.I.Rainina, T.A.Makhlis, V.I.Lozinsky, S.D.Varfolomeyev. Applied
Biochemistry and Biotechnology, 1992. Vol. 36, pp. 199-210.
A Flow-Through Enzyme
Analyzer for Determination of L-Lysine Concentration, Biosensors and
Bioelectronics, 1991. A. L. Simonian, G.E.Khachatrian,
S.Sh.Tatikian, Ts.M.Avakian, I.E.Badalian. Vol.6, No. 2, pp. 93-99.
Kinetic Properties of
Bacterial Urate Oxidase Entrapped in Hydrated Reversed Micelles,
E.A.Malakhova, N.A.Chebotareva, B.I.Kurganov, A. L. Simonian.
Biological Membranes (Russian). 1991. Vol.8, No.5, pp.453-459.
Incorporation of
Water-Soluble Enzymes Glucoseoxidase and Urate Oxidase Into Lecithin
Liposomes, T.G.Ambartzumyan, S.Ja.Adamian, L.S.Petrosian, A. L.
Simonian. Biological Membranes (Russian). 1991. Vol.8, No.12,
pp.1254-1259.
Kinetic Properties and
Termoinactivation of Bacterial Uricas, A. L. Simonian,
S.Sh.Tatikian, J.J.Kulys. Biochemistry (Russian). 1985. Vol. 50,
No. 5, pp.782-785.
Determination of Uric
Acid in Biological Solution Using Bienzyme Electrode, J.J.Kulys,
M.V.Pesliakene, V.A.Laurinavicus, S.Sh.Tatikian, A. L. Simonian.
Journal of Analytical Chemistry (Russian). 1985. Vol.XL, No 11,
pp.2077-2080
Application of
immobilized glucose oxidase and urat oxidase in analytical systems,
A. L. Simonian, S.Sh.Tatikian, G. Khachatryan. Applied
Biochemistry and Microbiology (Russian), 1986, Vol. 12 (6) pp.
675-679.
An Enzyme-based
Biosensors for Direct and Discriminative Detection of CW Nerve Agents
and Agricultural Pesticides”, A. Simonian and J. Wild, a chapter in
“Advances in Homeland Security, Vol. 1. edited by: Sandy Amass, Arun
Bhunia, Alok Chaturvedi, Dan Dolk, Srinivas Peeta, Mike Atallah Purdue
University Press. Invited publication, 2006.
Enhancement of the
Specificity of an Enzyme-based Biosensor for L-Tryptophan, A. L.
Simonian, E. I. Rainina, P. F. Fitzpatrick, and J. R Wild.
“Tryptophan, Serotonin, Melatonin – Basic Aspects and Applications”,
Edited by Gerald Huether, Walter Kochen, Thomas J. Simat, Hans
Steinhart, Kluwer Academic/Plenum Publishers, Series: Advances in
Experimental Medicine and Biology, New York and London, 1999, pp
833-840.
Microbial Biosensors
Based on Potentiometric Detection, A. Simonian, E. Rainina, and J. Wild,
"Enzyme and Microbial Biosensors. Techniques and Protocols", A.
Mulchandani and K. Rogers Eds., Humana Press (Totowa, New Jersey), 1998,
237-248.
Metabolite Alternative
Splitting by Different Enzymes, A. L. Simonian, I.E.Badalian,
Smirnova I.P., Berezov T.T. Biochemical Engineering-Stuttgart.
Editor M.Reuss. G.Fisher Pub., Stuttgart-New York, 1991. pp. 344-347.
Patents
Smart Surface for
Monitoring Selected Physicochemical Properties and Method of
Preparation, Aleksandr L. Simonian, Vitaly J. Vodyanoy, Madhumati
Ramanathan. AU Technology Disclosure (AU #
06-031).
System and Method for Detection of Microorganisms Using
Lytic Phage. A. Simonian, I. Sorokulova, V. Vodyanoy. AU
Technology Disclosure (AU# 05-025). Method of L-proline
quantitative determination, Simonian, Aleksandr Lyudvigovic;
Rainina, Evgeniya I.; Badalyan, Irina Emilevna; Makhlis, Tatyana A.;
Tatikyan, Stepan Shagenovich; Khachatryan, Garnik Eduardovich. Russ.
Patent (1997), CODEN: RUXXE7 RU 2086652 C1 19970810 CAN
128:86154 AN 1998:76544 The method for uric
acid concentration determination, J.J.Kulys, M.V.Pesljakene,
V.A.Laurinavichus, A. L. Simonian, G.E.Khachatrian,
S.Sh.Tatikian, Ts.M.Avakian.
USSR Patent
# 1236378, February 8,
1986. Pseudomonas Putida VKM
B-1458 - a new strain-producer of L-lysine-2-monooxygenase,
A.L.Simonian, G.E.Khachatrian, S.Sh.Tatikian, Ts.M.Avakian,
G.E.Khachatrian.
USSR Patent
# 1310427, May 12,
1986. The method of L-lysine
concentration determination, A.L.Simonian, G.E.Khachatrian,
S.Sh.Tatikian, Ts.M.Avakian,
USSR Patent
# 1387417, June 5,
1987. Bacillus Fastidiosus
strain - producer of urate oxidase, I.B.Seiranian, E.G.Afrikian,
A.L.Simonian, S.Sh. Tatikian, N.I.Mkrtchian, Ts.M.Avakian.
USSR Patent
#1482196, January 22 1989.
Review Articles
and Book Chapters
Flow-Injection
Analytical System Based on Column Mini-Reactors, A. L. Simonian. In
Monograph "Biotechnics - a Novel Strategy of Computerization"
(Russian) 1991. Ed.Yu.Akhapkin, S.I.Barstev et al. Moscow, Nauka,
pp.87-95.
Enzyme-based Analytical System in
Analytical Practice – Reality and Perspectives. A. L. Simonian, and E.
M. Akopyan, Review Information Series, USSR Ministry of Medical and
Biotechnological Industry, Moscow, 1990.