Dr. RAM B. GUPTA
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The Philpott-Westpoint Stevens Distinguished chair Professor Department of Chemical
Engineering Auburn, |
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Books
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Ram B. Gupta, U.B. Kompella (eds.) Nanoparticle Technology for Drug Delivery Taylor & |
Ram B. Gupta, J.J. Shim Solubility in Supercritical Carbon Dioxide CRC Press,
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M.E. Prudich, H. Chen, T. Gu, Ram B. Gupta, K. P. Johnston, H. Lutz, G. Ma, Z. Su Perry's Chemical Engineers' Handbook 8/E Section 20:Alternative Separation Processes McGraw-Hill Professional, |
Ram B. Gupta (ed.) Hydrogen
Fuel: Production, Storage, and Transport CRC Press, |
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Research Interests
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Pharmaceuticals |
Energy and Fuels |
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· Supercritical carbon dioxide technology · Nanotechnology · Nanoparticles · Nanomedicine · Controlled release · Nanomixing · Particle handling ·
Smart medicine |
· Supercritical water technology · Hydrogen fuel · Renewable fuels · Bio-energy · Liquid fuels from biomass · Cellulose and lignin de-polymerization · Cellulosic gasoline, ethanol and diesel · CO2 sequestration |
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Education
Post-doc (1995),
Chemical Engineering, University of
California,
Ph.D. (1993),
Chemical Engineering, University of Texas,
M.S. (1989),
Chemical Engineering, University
of Calgary,
B.E. (1987), Chemical Engineering, Indian Institute of Technology (formerly
University of Roorkee), Roorkee,
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Board and
Consulting Positions
2008
– Member of Editorial Board, Journal
of Nanotechnology
2008 – Member of Editorial Board, Research Letters in Chemical Engineering journal
2008 – Member of Editorial Board, Research Letters in Nanotechnology journal
2005 – Member of Editorial Board, Journal of Biomedical Nanotechnology journal
2005 – 07 Member of Editorial Board, Nanomedicine: Nanotechnology, Biology and Medicine journal
2004 –
Member of Engineering Faculty Council,
2004 – 06 Member of Editorial Advisory Board, Industrial & Engineering Chemistry Research journal
2002 – 07 Member of
Patent and Invention Disclosure Review Committee,
2001 – Consultant to five major chemical and pharmaceutical companies
2000 – 01 President,
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Honors and Awards
1. Fellow of
2.
3. DuPont Science and Engineering Awards (2002, 2003, 2004)
4. Who’s Who in Nanotechnology (nanovantage.com, 2004)
5. Auburn Alumni Engineering Council Senior Faculty Research Award (2002)
6. James A. Shannon Director’s Award, The National Institutes of Health (1998)
7. Auburn Alumni Engineering Council Junior Faculty Research Award (1998)
8.
9. Professional
Development Award,
10. President CSChE Graduate Chapter, University of
11. United Nations' Youth Ambassador to
12. Dr. N. Gopalkrishna Silver Medal, IIT Roorkee (1987)
15. Second Prize in All
16. Second Prize in All
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Book Chapters
14. Gupta,
R.B.; Pant, K.K., Fundamentals and Use of Hydrogen as a Fuel, in Hydrogen Fuel: Production, Transport and Storage, CRC Press,
13. Gupta, R.B.; Pant, K.K., Hydrogen
Storage in Metal Hydrides,
in Hydrogen Fuel: Production,
Transport and Storage, CRC Press,
12. Gupta, R.B.; Pant, K.K., Hydrogen
Storage in Carbon Materials,
in Hydrogen Fuel: Production,
Transport and Storage, CRC Press,
11. Gupta, R.B.;
Johnston, K.P., Supercritical Fluid Separation Processes, Section 20 in Perry’s Chemical Engineers’ Handbook 8th
edition, McGraw Hill, 2008.
10. Cai, W.; Gupta, R.B., Hydrogel,
in Kirk-Othmer Encyclopedia of Chemical Technology,
Concise 5th edition, John Wiley & Sons, New York, 2007.
9. Gupta, Ram B.. Polymer or protein stabilized nanoparticles from emulsions. Drugs and the Pharmaceutical Sciences (2006), 159 (Nanoparticle Technology for Drug Delivery), 85-102.
8. Gupta, Ram B.. Supercritical fluid technology for particle engineering. Drugs and the Pharmaceutical Sciences (2006), 159 (Nanoparticle Technology for Drug Delivery), 53-84.
7. Gupta, Ram B.. Fundamentals of drug nanoparticles. Drugs and the Pharmaceutical Sciences (2006), 159 (Nanoparticle Technology for Drug Delivery), 1-19.
6. Gupta, R.B.; Johnston, K.P., Supercritical Fluid Separation Processes, Section 20 in Perry’s Chemical Engineer’s Handbook 8th edition, McGraw Hill, 2008.
5. Gupta R.B., Supercritical Water Oxidation, in Encyclopedia of Chemical Processing, Marcel Dekker, 2005.
4. Gupta R.B., Supercritical Fluid Extraction, in Encyclopedia of Chemical Processing, Marcel Dekker, 2005.
3. Gupta, R.B., Supercritical CO2 and H2O Based Technologies for Zero Discharge, in Process Pollution Prevention Towards Zero Discharge, edited by T. Das, Wiley Interscience, Hoboken, NJ, 2005, pages 406-415.
2. Bandi, N.; Gupta, Ram B.; Roberts, Christopher B.; Kompella, Uday B., Formulation of Controlled-Release Drug Delivery Systems in “Supercritical Fluid Technology for Drug Product Development” Eds. Peter York, Uday B. Kompella, and Boris Shekunov, Marcel Dekker, New York, 2004, pages 367-410.
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Cai, W.; Gupta, R.B., Hydrogel, in Kirk-Othmer
Encyclopedia of Chemical Technology, John Wiley & Sons,
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Patents
1.
Gupta, R.B.; Chattopadhyay,
P. Method of forming nanoparticles
and microparticles of controllable size using
supercritical fluids with enhanced mass transfer, US Patent 6,620,351;
2. Gupta, Ram B.; Chattopadhyay, Pratibhash, Method for Manufacture of Fine Particles, WO02093132 (2002)
3. Elton, David J.; Gupta, Ram B., “Water Stabilization Using Microparticles”, PCT application filed August 1, 2008
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Laboratory Equipment
Dr. Gupta’s laboratory is in rooms
205, 206, 222 Wilmore in the
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Graduate Students and Postdocs
Current Graduate Students: Adam Byrd, Ganesh Sanganwar, Melinda Hemingway, Sandeep Kumar
Current Visiting Scholars: Dr. Lingzhao Kong
Current Undergraduate Research Students:
Former Graduate Students: Pratibhash Chattopadhyay (Ferro Corporation, Cleveland, OH), Poongunran Muthukumaran (Aspen Aerogel, Inc., MA), Ray L. Brinkley (Southern Testing and Research Laboratory, Wilson, NC), Michael Dubbs (3M, Decatur, AL), James D. Seymour (Walk Haydel, New Orleans, LA), Rajesh Kumar (Alkermes, Inc. Cambridge , MA), Eric Anderson (Merck & Co., Elkton, VA), Raghu Vishawnathan (Materials Engineering, Auburn University), Amol Thote (Bayer Healthcare Pharmaceuticals, Emeryville, CA), Ranjit Thakur (Novartis, Basel, Switzerland) , Jayant Gadhe (Larson & Turbo – Chiyoda, Mumbai, India), Kayoko Ono (Medtronics, Tokyo, Japan).
Outstanding PhD Students (Award
by
Former Visiting Scholars: Dr. Cai Wensheng, Demitri Varlamov, Jose Francisco Louvier, Prof. Jae-Jin Shim, Prof. K.K. Pant, Prof. Ahyan Demirbas
Former Undergraduate Research Students: Keeley Greynolds, Deandra Miller, Len Pritchett, Jeremy Brooks , Adam Anderson, Daniel Lilly, Deepak Sree, Harvey Barnett, John Chappel, Kate Wilbank, Sheena Lewis, Thushari Abesingha, Haley Brooks, Suhaila Rowe, Auburn Hudgins, Hailey Capps, Alisha Peterson, Scott Novack, Stacy Sommerfield, James Craig Smith
Group Pictures:
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Selected Publications
68. Sanganwar, Ganesh P.; Gupta, Ram B.; Ermoline, Alexandre; Scicolone, James V.; Dave, Rajesh N. Environmentally benign nanomixing by sonication in high-pressure carbon dioxide. Journal of Nanoparticle Research (2009), 11(2), 405-419. more details
67. Kumar, Sandeep; Gupta, Ram B.. Hydrolysis of Microcrystalline Cellulose in Subcritical and Supercritical Water in a Continuous Flow Reactor. Industrial & Engineering Chemistry Research (2008), 47(23), 9321-9329. more details
66. Sanganwar, Ganesh P.; Gupta, Ram B.. Dissolution-rate enhancement of fenofibrate by adsorption onto silica using supercritical carbon dioxide. International Journal of Pharmaceutics (2008), 360(1-2), 213-218. more details
65. Byrd, Adam J.; Pant, K. K.; Gupta, Ram B.. Hydrogen production from glycerol by reforming in supercritical water over Ru/Al2O3 catalyst. Fuel (2008), 87(13-14), 2956-2960. more details
64. Sanganwar, Ganesh P.; Gupta, Ram B.. Enhancement of shelf life and handling properties of drug nanoparticles: nanoscale mixing of itraconazole with silica. Industrial & Engineering Chemistry Research (2008), 47(14), 4717-4725. more details
63. Byrd, Adam J.; Pant, K. K.; Gupta, Ram B.. Hydrogen Production from Ethanol by Reforming in Supercritical Water Using Ru/Al2O3 Catalyst. Energy & Fuels (2007), 21(6), 3541-3547. more details
62. Gadhe, Jayant B.; Gupta, Ram B. Hydrogen production by methanol reforming in supercritical water: Catalysis by in-situ-generated copper nanoparticles. International Journal of Hydrogen Energy (2007), 32(13), 2374-2381. more details
61. Byrd, Adam J.; Pant, K. K.; Gupta, Ram B. Hydrogen Production from Glucose Using Ru/Al2O3 Catalyst in Supercritical Water. Industrial & Engineering Chemistry Research (2007), 46(11), 3574-3579. more details
60. Quintero-Ortega, Iraís A.; Vivaldo-Lima, Gupta, Ram B.; Eduardo; Luna-Bárcenas, Gabriel; Penlidis, Alexander, Modeling of the Homogeneous Free-Radical Copolymerization Kinetics of Fluoromonomers in Carbon Dioxide at Supercritical Conditions, Journal of Macromolecular Science w, Part A: Pure and Applied Chemistry (2007) 44, 205–213. more details
59. Thakur, Ranjit; Gupta, Ram B., Rapid expansion of supercritical solution with solid cosolvent (RESS-SC) process: Formation of 2-aminobenzoic acid nanoparticle, Journal of Supercritical Fluids (2006), 37, 307-315. more details
58. Thakur, Ranjit; Gupta, Ram B.. Formation of phenytoin nanoparticles using rapid expansion of supercritical solution with solid cosolvent (RESS-SC) process. International Journal of Pharmaceutics (2006), 308(1-2), 190-199. more details
57. Gadhe, Jayant B.; Gupta, Ram B.; Elder, Thomas. Surface modification of lignocellulosic
fibers using high-frequency ultrasound.
Cellulose (
56. Thote Amol J; Gupta Ram B Formation of nanoparticles of a hydrophilic drug using supercritical carbon dioxide and microencapsulation for sustained release. Disease-a-month : DM (2005), 51(6), 362-73. more details
55. Thakur, Ranjit; Gupta, Ram B. Rapid Expansion of Supercritical Solution with Solid Cosolvent (RESS-SC) Process: Formation of Griseofulvin Nanoparticles. Industrial & Engineering Chemistry Research (2005), 44(19), 7380-7387. more details
54. Thakur, Ranjit; Gupta, Ram B. Supercritical CO2 Based Silica Coating of Gold Nanoparticles Using Water-in-Oil Microemulsions. Industrial & Engineering Chemistry Research (2005), 44(9), 3086-3090. more details
53. Thote, Amol J.; Chappell, John T., Jr.; Gupta, Ram B.; Kumar, Rajesh. Reduction in the initial-burst release by surface crosslinking of PLGA microparticles containing hydrophilic or hydrophobic drugs. Drug Development and Industrial Pharmacy (2005), 31(1), 43-57. more details
52. Flores-Ramírez, Nelly.; Eduardo A. Elizalde- Peña; Gabriel Luna-Bárcenas; Salomón R. Vásquez-García; Jesús González-Hernández; Agustín Martinez-Ruvalcaba; Isaac C. Sanchez; Ram B. Gupta, “Characterization and Degradation of Functionalized Chitosan with Glycidyl Methacrylate,” Journal of Biomaterials Science, Polymer Edition, April 2005, vol. 16, iss. 4, pp. 473-488(16) 2005. more details
51. Thakur, R.;
Gupta, Ram B. “Production of Hydrocortisone Micro- and Nano-particles
using Supercritical Antisolvent with Enhanced Mass
Transfer, Chem. Eng. Comm., 193:293–305, 2006. more details
50. Louvier-Hernández,
José F.; Luna-Bárcenas G.; Thakur,
R.; Gupta, Ram B. “Formation of chitin nano-fibers by supercritical antisolvent,”
Journal of Biomedical Nanotechnology, vol 1, pages
1-6, January 2005. more
details
49. Thote, A.;
Gupta, Ram B. “Formation of Nanoparticles of a
Hydrophilic Drug using Supercritical CO2 and Microencapsulation
for Sustained Release,” Nanomedicine: Nanotechnology, Biology and Medicine, 1,
85-90, 2005. more details
48. Gadhe, Jayant B.; Gupta, Ram B.,
“Hydrogen Production by Methanol Reforming in Supercritical Water:
Suppression of Methane Formation” Industrial &
Engineering Chemistry Research (2005) 44, 4577-4585. more details
47. Cai, Wensheng; Gupta, Ram B.. Molecularly-imprinted polymers selective for tetracycline binding. Separation and Purification Technology (2004), 35(3), 215-22. more details
46. Thote, Amol; Gupta, Ram, B. Hydrogen-bonding of a Dichroic Dye with a Liquid Crystal for Application to LCDs. Fluid Phase Equilibria (2004), 220(1), 47-54. more details
45. Viswanathan, R.; Lilly, G. D.; Gale, W. F.; Gupta, R. B Formation of Zinc Oxide-Titanium Dioxide Composite Nanoparticles in Supercritical Water, Industrial & Engineering Chemistry Research (2003), 42(22), 5535-5540. more details
44. Bell, Philip W.; Thote, Amol J.; Park, Yoonkook; Gupta, Ram B.; Roberts, Christopher B. Strong Lewis Acid-Lewis Base Interactions between Supercritical Carbon Dioxide and Carboxylic Acids: Effects on Self-association. Industrial & Engineering Chemistry Research (2003), 42(25), 6280-6289. more details
43. Thote, Amol J.; Gupta, Ram B.. Hydrogen-Bonding Effects in Liquid Crystals for Application to LCDs. Industrial & Engineering Chemistry Research (2003), 42(6), 1129-1136. more details
42. Viswanathan, Raghu; Gupta, Ram B. Production of Zinc Oxide Nanoparticles in Supercritical Water, Journal of Supercritical Fluids, 2003, 27, 187-193. more details
41. Chattopadhyay,
Pratibhash; Gupta, Ram B. Supercritical CO2 based Formation
of Silica Nanoparticles Using Water-in-Oil Microemulsions.
Ind.
40. Cai, Wensheng; Gupta, Ram B. Thermosensitive and Ampholytic Hydrogel for Salt Solution. in press, J. Appl. Polym. Sci. (2003). more details
39. Chattopadhyay, Pratibhash; Gupta, Ram B. Supercritical CO2 Based Production of Magnetically Responsive Micro- And Nanoparticles For Drug Targeting., Ind. Eng. Chem. Res., (2002), 41(24), 6049-6058. more details
37. Muthukumaran, P.; Brinkley, R.L.; Gupta, Ram B. Lattice-fluid equation of state with hydrogen-bond cooperativity. AIChE J. (2002), 48, 386-392. more details
36. Chattopadhyay, P.; Gupta, Ram B. Protein nanoparticles formation by supercritical antisolvent with enhanced mass transfer. AIChE J. (2002), 48, 235-244. more details
35. Cai, Wensheng; Gupta, Ram B. Fast-responding bulk hydrogels with microstructure. J. Appl. Polym. Sci. (2002), 83(1), 169-178. more details
34. Chattopadhyay, P.; Gupta, R. B. Production of griseofulvin nanoparticles using supercritical CO2 antisolvent with enhanced mass transfer. Int. J. Pharm. (2001), 228(1-2), 19-31. more details
33. Chattopadhyay,
Pratibhash; Gupta, Ram B. Production of Antibiotic Nanoparticles
Using Supercritical CO2 as Antisolvent with Enhanced
Mass Transfer.
32. Cai, Wensheng; Gupta, Ram B.
Poly(N-ethylacrylamide) hydrogels
for lignin separation.
31. Brinkley, Ray L.; Gupta, Ram B. Hydrogen bonding with aromatic rings. AIChE J. (2001), 47(4), 948-953. more details
30. Cai, Wensheng; Anderson, Eric C.; Gupta, Ram B. Separation of lignin from aqueous mixtures by
ionic and nonionic temperature-sensitive hydrogels.
29. Betageri,
Guru V.; Deshmukh, Deepali
V.; Gupta, Ram B. Oral sustained-release
bioadhesive tablet formulation of didanosine. Drug
28. Kumar, Rajesh; Gupta, Ram B.; Betageri, Guru V. Formulation, characterization, and in vitro release of glyburide from proliposomal beads. Drug Delivery (2001), 8(1), 25-27. more details
27. Muthukumaran,
Poongunran; Gupta, Ram B. Sodium-Carbonate-Assisted Supercritical Water
Oxidation of Chlorinated Waste.
26. Chattopadhyay,
Pratibhash; Gupta, Ram B. Supercritical CO2-Based Production of
Fullerene Nanoparticles.
25. Martin, Todd M.; Gupta, Ram B.;
Roberts, Christopher B. Measurements and
modeling of cloud point behavior for poly(propylene glycol) in ethane and in
ethane + cosolvent mixtures at high pressure.
24. Muthukumaran, Poongunran; Gupta, Ram B.; Sung, Hwan-Do; Shim, Jae-Jin; Bae, Hyo-Kwang. Dye solubility in supercritical carbon dioxide. Effect of hydrogen bonding with cosolvents. Korean J. Chem. Eng. (1999), 16(1), 111-117. more details
23. Diskin, C.J.; Gupta, Ram B.; Ravis, W.R.; Stokes, T.J.; Dansby, L.M.; Carter, T.B. Edema, Oncotic Pressure and Entropy: Novel Considerations for the Treatment of Edema Through Attention to Thermodynamics. Nephron (1998) 78, 131-138. more details
22. Kumar, Rajesh; Reznik, D.A.; Gupta, Ram B.; Betageri, Guru V. The Stability of Amphotericin-B in a Mixture of Fungizone® and Optimoist® Int. J. Pharm. Compounding (1998) Vol. 2, No. 4, July/August. more details
21. Brinkley, Ray L.; Gupta, Ram B.. Intra- and Intermolecular Hydrogen Bonding of
2-Methoxyethanol and 2-Butoxyethanol in n-Hexane.
20. Gorbaty,
Yu. E.; Gupta, Ram B.. The Structural
Features of Liquid and Supercritical Water.
19. Dubbs, Michael D.; Gupta, Ram B.. Solubility of Vitamin E (a-Tocopherol) and Vitamin K3 (Menadione) in Ethanol-Water Mixture. J. Chem. Eng. Data (1998), 43(4), 590-591. more details
18. Kumar, Rajesh; Betageri, Guru V.; Gupta, Ram B.. Partitioning of oxytetracycline between aqueous and organic solvents Effect of hydrogen bonding. Int. J. Pharm. (1998), 166(1), 37-44. more details
17. Kumar, Rajesh; Betageri, Guru V.; Gupta, Ram B.. Phase behavior of mixtures containing antibiotics. Effect of hydrogen bonding on tetracycline partitioning. Fluid Phase Equilib. (1998), 143(1-2), 99-109. more details
16. Gupta, Ram B.; Brinkley, Ray L. Hydrogen-bond cooperativity in 1-alkanol + n-alkane binary mixtures. AIChE J. (1998), 44(1), 207-213. more details
15. Gupta, Ram B. Do short and slim people
live longer? An engineering perspective, MADHYA: The Midage,
14. Seymour, James D.; Wallace, Henry C.; Gupta, Ram B. Sonochemical reactions at 640 kHz using an efficient reactor. oxidation of potassium iodide. Ultrason. Sonochem. (1997), 4(4), 289-293. more details
13. Gupta, Ram B.; Kumar, Rajesh; Betageri, Guru V.
Phase Behavior of Mixtures Containing Antibiotics. Chloramphenicol
Partitioning.
12. Seymour, James D.; Gupta, Ram
B.. Oxidation of Aqueous Pollutants
Using Ultrasound: Salt Induced Enhancement.
11. Veytsman, Boris A.; Gupta, Ram B.. Fluctuation theory of hydrogen bonding in near-critical fluids. AIChE J. (1996), 42(9), 2661-2667. more details
10. Gupta, Ram B.; Prausnitz, John M. Vapor-liquid equilibria for copolymer/solvent systems: effect of "intramolecular repulsion". Fluid Phase Equilib. (1996), 117(1-2), 77-83. more details
09. Gupta, Ram B.; Prausnitz,
John M. Vapor-Liquid Equilibria
for Solvent-Polymer Systems from a Perturbed Hard-Sphere-Chain Equation of
State.
08. Gupta, Ram B.; Prausnitz, John M. Vapor-Liquid Equilibria of Copolymer + Solvent and Homopolymer + Solvent Binaries: New Experimental Data and Their Correlation. J. Chem. Eng. Data (1995), 40(4), 784-91. more details
07. Gupta, Ram B.; Johnston, Keith P. Lattice fluid hydrogen bonding model with a local segment density. Fluid Phase Equilib. (1994), 99(1-2), 135-51. more details
06. Gupta, Ram B.; Johnston, Keith
P. Ion Hydration in Supercritical
Water.
05. Gupta, Ram B.; Han, Chae J.; Johnston, Keith P. Recovery of proteins and amino acids from reverse micelles by dehydration with molecular sieves. Biotechnol. Bioeng. (1994), 44(7), 830-6. more details
04. Kazarian, Sergei G.; Gupta, Ram B.; Clarke, Matthew J.; Johnston, Keith P.; Poliakoff, Martyn. How is hydrogen-bonding influenced by solvent density? The spectroscopic study and modeling of the interaction between a proton donor and acceptor from the gas phase to supercritical fluid states. J. Am. Chem. Soc. (1993), 115(24), 11099-109. more details
03. Gupta, Ram B.; Combes, James R.; Johnston, Keith P. Solvent effect on hydrogen bonding in supercritical fluids. J. Phys. Chem. (1993), 97(3), 707-15. more details
02. Gupta, Ram B.; Panayiotou, Constantinos G.; Sanchez, Isaac C.; Johnston, Keith P. Theory of hydrogen bonding in supercritical fluids. AIChE J. (1992), 38(8), 1243-53. more details
01. Gupta, Ram B.; Heidemann, Robert A. Solubility models for amino acids and antibiotics. AIChE J. (1990), 36(3), 333-41. more details
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Last Revised: Feb 2009